Sophie Paczesny, MD, PhD, is the Nora Letzter Professor of Pediatrics and immunology, a full member of the Indiana University Simon Cancer Center, and leads the Biomarkers Stem Cell Transplantation Program. She received her MD degree at the University of Strasbourg, and obtained her PhD in Tumor Immunology from the University of Paris and The Baylor Institute for Immunology, Dallas, TX. In 2006, she moved to the University of Michigan where she deployed proteomics to discover biomarkers for the outcomes following allogeneic hematopoietic cell transplantation, and continued this work at Indiana University. She is councilor of the American Society for Clinical Investigation, co-chair of the Center for International Blood and Marrow Transplant immunobiology working group, co-chair on the ASH task force on immunotherapies, and co-chair of the TCT committee on diversity. Dr. Paczesny’s research has focused on three areas: 1) developing and translating biomarkers of graft versus host disease and graft versus tumor; 2) discovering inhibitors of drug targetable biomarkers; and 3) finding novel immunotherapies with a recent focus on targeting the ST2/IL-33 pathway.