Accelerating Cell & Gene Therapy Adoption:
Proof of Concept to Standard of Care

Plenary and Satellite Sessions
Translational Research
Clinical Translation
Commercialization
Hot Topics Sessions
Strategies for Commercialization Track
Quality and Operations Track

TUESDAY MAY 26

07:00 – 17:00
FACT Cord Blood Inspection and Accreditation Workshop

16:00 – 19:00
ISCT 2020 Registration Open

WEDNESDAY MAY 27 - Pre-Conference Day

PRECONFERENCE TRACKS

MSC​

CO-CHAIRS
Jacques Galipeau, MD
University of Wisconsin-Madison (US)

Mauro Krampera, MD
University of Verona (IT)

Luc Sensebe, MD, PhD
ISCT MSC Committee (FR)

Cell Processing

CO-CHAIRS
Ruud Hulspas, PhD
Cellular Technologies Bioconsulting, LLC (NL)

Mara Neal, SH(ASCP)MT, MS, MBA
Cook Biotech (US)

Vicki Antonenas, MSc
Westmead Hospital
(AU)

Paul Wallace, PhD
Roswell Park Comprehensive Cancer Center (US)

08:30 – 10:00
Collection and Starting 
Materials

10:15 – 11:45
Cell Selection & Gene Editing

13:00 – 14:30
Cell Activation and
Expansion

14:45 – 16:15
Product Characterization, just before product goes to patient

Global Regulatory Perspectives

CO-CHAIRS
Karen Nichols, Esq.
Magenta Therapeutics (US)

Dominic Wall, PhD, FFSc (RCPA)
Cell Therapies Pty Ltd, Peter MacCallum Cancer Centre (AU)

08:00 – 08:30
Regulatory Roundup

08:30 – 10:00
Sterility Controls –
Past, Present, Future

10:15 – 11:45
Issues related to product administration at the clinical site

13:00 – 14:30
Combination Products (Biologics/Devices)

14:45 – 16:15
Topic TBC

Investigators to Investors
(i to i)

CO-CHAIRS
Bill Milligan
Steminent Biotherapeutics (CA/TW)

Patrick Rivers
Aquilo Capital (US)

Program under development

ISCT-Cord Blood Connect
In partnership with WMDA

CO-CHAIRS
Elizabeth J. Shpall, MD
MD Anderson Cancer Center (US)

Joanne Kurtzberg, MD
Carolina’s Cord Blood Bank Duke University Medical Center (US)

Ngaire Elwood, PhD
BMDI Cord Blood Bank and Murdoch Children’s Research Institute (AU)

08:30 – 10:00
Cord Blood Breaking News

10:15 – 11:45
Cord Blood Immunotherapy

13:00 – 14:30
Cord Tissue Derived MSCs

14:45 – 16:15
Cord Blood Derived Regenerative Medicine

Gene Therapy

CHAIR
Sandeep Soni, MD
Stanford University (US)

08:30 – 10:00
Lentiviral Gene Therapy Approaches

10:15 – 11:45
Advances in Gene Therapy Technologies & Applications Part I

13:00 – 14:30
CMC Requirements & Considerations

14:45 – 16:15
Advances in Gene Therapy Technologies & Applications Part II

ISCT-FACT Quality Bootcamp

Program under development


Corporate Symposia

16:30 – 18:30

Technology Symposium

Druck

 16:30 – 18:30

Technology Symposium

Thermo-Fisher-COLOR-CMYK

19:00 – 19:30

President’s Welcome Address

J. Rasko_cropped

John Rasko, AO, BSc(Med), MBBS(Hons), PhD
University of Sydney (AU)

ISCT President

capecchi_cropped

Mario Capecchi, PhD
University of Utah (US)

2007 Nobel Laureate
(Physiology or Medicine)

C. Chabbanon_cropped

Christian Chabannon, MD, PhD
Institut Paoli Calmettes (FR)
ISCT 2020 Co-Chair

R. Ciccocioppo_cropped

Rachele Ciccocioppo, MD
University of Verona 
(IT)
ISCT 2020 Co-Chair

I. Martin_cropped

Ivan Martin, PhD
University Hospital Basel 
(CH)
ISCT 2020 Co-Chair

19:30 – 21:00

Exhibit Open House and Welcome Reception

Open to all registered delegates, enjoy a glass of wine, hors d’oeuvres, and the opportunity to mingle and network
with peers from all over the globe. 
Make new connections and discover the latest innovations and services from our exhibitors.  

Global Showcase Theatre (Exhibit Hall)

19:45 – 20:00

20:00 – 20:15
Sexton Biotechnologies

20:15 – 20:30 

THURSDAY MAY 28 - Day One Main Meeting

07:30 - 08:30
Hot Topics Session

Regenerative Medicine in Digestive Diseases: State of the Art, Open Needs and Next Steps

C0-CHAIRS
Basak E. Uygun, PhD
Massachusetts General Hospital and Harvard Medical School (US)
Giuseppe Orlando, MD, PhD 
Wake Forest University School of Medicine (US)

SPEAKERS
Khalil N. Bitar, PhD
Wake Forest University School of Medicine (US)
Vincenzo Cardinale, MD, PhD
Sapienza University of Rome (IT)
Pedro Baptista, PharmD, PhD
Madrid University and Aragon Institute for Health Research (ES)

See Session Details

07:30 - 08:30
Hot Topics Session

Gene Edited and Engineered Cell Based
Therapeutics for Cancer

CO-CHAIRS
Khalid Shah, MS, PhD
Harvard Medical School (US)
Massimo Dominici, MD
University of Modena and Reggio Emilia (IT)

See Session Details

07:30 - 08:30
Corporate Session

Breakfast Tutorial Hosted by

08:30 – 10:30

Opening Remarks
ISCT Career Achievement Award Presentation

Presidential Plenary
Mastering Pluripotent Cells with Therapeutic Intent

See Session Details

CHAIR

J. Rasko_cropped

John Rasko, AO, BSc(Med), MBBS(Hons), PhD
University of Sydney (AU)

translational research_cropped
capecchi_cropped

Mario Capecchi, PhD 
University of Utah (US)

2007 Nobel Laureate (Physiology or Medicine)
Keynote speaker sponsored by Cytotherapy, The official journal of the International Society for Cell & Gene Therapy

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M. Pechanski_cropped

Marc Peschanski, MD, PhD 
I-Stem (FR)

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R. Jaenisch_cropped

Rudolf Jaenisch, MD   
Whitehead Institute and Massachusetts Institute of Technology (US)

Break

10:30 – 11:00
Coffee Break with Exhibits and Corporate Sessions

Global Showcase Theatre (Exhibit Hall)

10:30 – 10:45 

10:45 – 11:00

11:00 - 12:15
Plenary Satellite 1a

iPSC for Cardiovascular Disease

CHAIR
Daniel J. Weiss, MD, PhD
University of Vermont (US)

SPEAKER
Massimiliano Gnecchi, MD, PhD
University of Pavia & IRCCS Policlinico San Matteo (IT)
Philippe Menasché, MD, PhD 
University Paris Decartes (FR)

See Session Details

11:00 - 12:15
Plenary Satellite 2a

MSC Mechanism of Action

CHAIR
Jacques Galipeau, MD
University of Wisconsin-Madison (US)

SPEAKER
Karin Tarte, PharmD, PhD
UMR INSERM U1236, CHU Rennes, EFS Bretagne (FR)

See Session Details

11:00 - 12:15
OC Session

Gene Therapy for Globin Disorders

SPEAKER
Marina Cavazzana, MD, PhD
Assistance Publique – Hôpitaux de Paris (FR)

11:00 - 12:15
Strategies for Commercialization

Innovating Process Development for Sustainable Manufacturing

CHAIR
Dominic Clarke, PhD
HemaCare Corp. (US)

SPEAKERS
Denis Bedoret, PhD
Masthercell (BE)
Stuart Curbishly, PhD
Birmingham University NHS Trust (UK)
Ricardo Batista, PhD
Cellectis (FR)

See Session Details

11:00 - 12:15
Quality & Operations

Qualification, Regulation of Gene Editing Tools in Cell & Gene Therapy

CHAIR
Shirley Bartido, PhD, MBA
Cellectis (US)

SPEAKERS
Christopher Ballas, PhD
Innovative Cellular Therapeutics (US)
David R. Jones, MSc
MHRA (UK)
Stephan Reynier, MSc
Cellectis (FR)

See Session Details

Break

12:15 – 13:45
Lunch with Exhibits and Corporate Sessions

Lunch & Learn Session
(Lunch Provided)

12:30 – 13:30


Lunch & Learn Session
(Lunch Provided)

12:30 – 13:30

 

Global Showcase Theatre (Exhibit Hall)

12:30 – 12:45

12:45 – 13:00  Cynata

13:00 – 13:15 

13:15 – 13:30 

13:45 – 15:15

Plenary
Mesenchymal Stromal Cells – Full Circle from Basic Research Insights to Clinical Trial Updates

See Session Details

CHAIR

S. Viswanathan_cropped

Sowmya Viswanathan PhD
University Health Network Cell Therapy (CA)

translational research_cropped
J. Galipeau_cropped

Jacques Galipeau, MD
University of Wisconsin-Madison (US)

clinical translation_cropped
H. Bonig_cropped

Halvard Bönig, MD, PhD
Johann-Wolfgang-Goethe University  (DE)

clinical translation_cropped
D. Farge Bancel_cropped

Dominique Farge Bancel, MD
Paris Diderot University and Hopital Saint-Louis (FR)

Break

15:15 – 15:45
Coffee Break with Exhibits and Corporate Sessions

Global Showcase Theatre (Exhibit Hall)

15:15 – 15:30 

15:30 – 15:45

 

15:45 - 17:00
Plenary Satellite 1b

iPSC Derived Organoids

 

15:45 - 17:00
Plenary Satellite 2b

Opportunities, Challenges and Tangible Progress in the Development of Efficacious Culture Expanded Cell Therapies for Musculoskeletal Disease

MODERATOR
George Muschler, MD
Cleveland Clinic (US)

SPEAKERS
Christian Jorgensen, MD, PhD
University Hospital Lapeyronie (FR)
Scott Rodeo, MD
The Hospital for Special Surgery (US)
Nicolas Piuzzi, MD
Cleveland Clinic (US)

See Session Details

15:45 - 17:00
OC Session

Success and Failure of Cell Therapy Clinical Trials for Acute and Chronic Lung Disease

CO-CHAIRS
Patricia R. M. Rocco, MD, PhD
Federal University of Rio de Janeiro (BR)

Claudia Dos Santos, MD
University of Toronto (CA)

SPEAKER
Patricia R. M. Rocco, MD, PhD
Federal University of Rio de Janeiro (BR)

Bernard Thébaud, MD
Ottawa Hospital Research Institute (CA)

Anthony Ting, PhD
Athersys, Inc. (US)

Daniel J. Weiss, MD, PhD
University of Vermont (US)

John Laffey, MD, MA, FCAI, FJFICMI
NUI Galway (IR)

15:45 - 17:00
Strategies for Commercialization

Raising Capital for CGT Industralization

CHAIR
Patrick Rivers, MBA
Aquilo Capital (US)

SPEAKER
Jak Knowles, MD
Leaps by Bayer (US)

Mark L. Bonyhadi, PhD
Qiming Venture Partners (US)

Sara Núñez-Garcia, PhD, MBA
Roivant Sciences (SUI)

See Session Details

15:45 - 17:00
Quality & Operations

Manufacturing Process Validation – Considerations for Validation of Autologous Products

CHAIR
Emily Hopewell, PhD
Indiana University School of Medicine (US)

SPEAKERS
Antonio Ruiz-Garcia, MPharm
Hospital Universitario Virgen de las Nieves (SP)
Aisha Khan, MSc, MBA
University of Miami (US)

Corey Smith, PhD
QIMR Berghofer (AU)

See Session Details

Corporate Sessions

17:00 – 19:00
Therapeutic Symposium

17:30 – 18:30
Technology Spotlight

Posters & Abstract Presentations

Poster Hall

18:00 – 19:30
Poster Session

Global Showcase Theatre (Exhibit Hall)

18:00 – 18:30
Abstract Elevator Pitch Session 1

FRIDAY MAY 29 - Day Two Main Meeting

07:30 - 08:30
Hot Topics Session

Long-Term Follow-up, Accreditation and Registries for
CAR-T Therapy (Joint Session with EBMT)

07:30 - 08:30
Hot Topics Session

Veterinary Medicine

CHAIR
Stéphane Maddens, PharmD, PhD, MBA
Vetiobank (FR)

SPEAKER
Nathalie Saulnier, PhD
Vetbiobank (FR)

Antonio J. Villatoro, DVM, PhD, MBA
ImmuneStem (SP)

See Session Details

07:30 - 08:30
Corporate Session

Breakfast Tutorial Hosted by

 

08:45 – 10:15

Plenary
Advances and Emerging Technologies in Immune-Mediated Cancer Treatments

 

See Session Details

CO-CHAIR

B. Levine_cropped

Bruce Levine, PhD
University of Pennsylvania (US)

CO-CHAIR

C. Chabbanon_cropped

Christian Chabannon, MD, PhD
Institut Paoli Calmettes (FR)

translational research_cropped
M. Maus_cropped

Marcela Maus, MD, PhD
Massachusetts General Hospital and Harvard Medical School (US)

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M. Hudacek_cropped

Michael Hudecek, MD
University of Würzburg (DE)

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K. Rezvani_cropped

Katy Rezvani, MD, PhD
MD Anderson Cancer Center (US)

Break

10:15 – 10:45
Coffee Break with Exhibits and Corporate Sessions

Global Showcase Theatre (Exhibit Hall)

10:15 – 10:30

10:30 – 10:45 

10:45 - 12:15
Plenary Satellite 3a

Immunotherapy Oral Abstracts

 

10:45 - 12:15
Plenary Satellite 4a

Industrializing Clinical Delivery

SPEAKERS
Jacqueline Barry, PhD
Cell and Gene Therapy Catapult (UK)

Aaron Dulgar-Tulloch, PhD
GE Healthcare (CA)

Gil Van Bokkelen, PhD
Athersys, Inc. (US)

See Session Details

10:45 - 12:15
OC Session

Imaging Cellular Therapeutics
(Joint Session with HESI CT-TRACS)

CHAIR
Brooke Helfer, PhD
Celsense Inc. (US)

SPEAKERS
Bettina Weigelin, PhD
Eberhard Karls University of Tübingen (DE)

Vidya Gopalakrishnan, PhD, MD
Anderson Cancer Center (US)

Jane Sosabowski, PhD
Barts Cancer Institute, Queen Mary University of London (UK)

10:45 - 12:15
Workshop

ISCT Presidential Task Force Session

SPEAKERS
Massimo Dominici, MD
University Hospital of Modena & Reggio Emilia – Modena Policlinic (IT)

Aaron Levine, PhD, Mphil
Georgia Tech (US)

Eva Rohde, Univ. Prof. Dr.
Department of Transfusion Medicine SALK (AT)


10:45 - 12:15
Strategies for Commercialization

Can we industrialize CAR T therapies? The practical challenges in achieving wide-spread patient access

CHAIR
Bill Milligan
Steminent Biotherapies (US/TW)

SPEAKERS
Gunther Busam, RPh, PhD 
Celgene (CH)

Elizabeth Hexner, MD
University of Pennsylvania (US)
Wen Bo Wang, PhD
Fate Therapeutics (US)
Suma Rao, PhD
Allogene Therapeutics (US)

See Session Details

10:45 - 12:15
Quality & Operations

Regulatory CMC Considerations of ATMPs

CHAIR
Paula Salmikangas, PhD
NDA Advisory Services Ltd. (FI)

SPEAKERS
Christopher Bravery, PhD
Consulting on Advanced Biologicals Ltd (UK)
Shinichi Noda, PhD
Pharmaceuticals and Medical Devices Agency (PMDA) (JP)
Rocio Salvador-Roldan
European Commission (BE)
 

 

See Session Details

Break

12:15 – 13:45
Lunch with Exhibits and Corporate Sessions

Lunch & Learn Session
(Lunch Provided)

12:30 – 13:30

 

Lunch & Learn Session
(Lunch Provided)

12:30 – 13:30

Global Showcase Theatre (Exhibit Hall)

12:30 – 12:45 
12:45 – 13:00 

13:00 – 13:15  Xcell Therapeutics

13:15 – 13:30   

 

13:45 – 15:15

Plenary
Is Big Pharma ready for industrial scale Cell and Gene Therapy?

See Session Details

CHAIR

A. Ting_cropped

Anthony Ting, PhD 
Athersys (US)

commercialization_cropped
E. Ostuni_cropped

Emanuele Ostuni, PhD
Novartis Oncology (CH)

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A. Krackhardt

Angela Krackhardt, MD
Technical University of Munich (DE)

commercialization_cropped
A. Santagostini_cropped

Alberto Santagostino, MBA
Lonza (CH)

Break

15:15 – 15:45
Coffee Break with Exhibits and Corporate Sessions

Global Showcase Theatre (Exhibit Hall)

15:15 – 15:30
Cell-Easy

15:30 – 15:45 

15:45 - 17:00
Plenary Satellite 3b

CAR-T for Solid Tumors

SPEAKER
Vivek K. Narayan, MD, MS
University of Pennsylvania (US)


15:45 - 17:00
Plenary Satellite 4b

Industrializing administration setting

CHAIR
Julie Murrell, PhD
MilliporeSigma (US)

SPEAKERS
Christopher Herbert, PhD
Leeds Teaching Hospitals NHS Trust (UK)
Anne Black
NHS Specialist Pharmacy Service (UK)
Christoph Demmerle
Novartis (DE)

See Session Details

15:45 - 17:00
Workshop

ISCT Chief Scientific Officer Abstract Showcase

15:45 - 17:00
Workshop

Early Stage Professionals Session

15:45 - 17:00
Strategies for Commercialization

Best practices for funding CGT startups from academia

CHAIR
Patrick Rivers, MBA
Aquilo Capital, (US)

SPEAKERS
Mike Milone, MD, PhD
Cabaletta Bio (US)

Patrick Hanley, PhD
Children’s National Medical Center (US)

See Session Details

15:45 - 17:00
Quality & Operations

Starting & Raw Material Selection for ATMP Manufacturing

CHAIR
Gloria Carmona, MPharm
Andalusian Network for Design and Translation of Advanced Therapies (ES)

SPEAKERS
Craig Spalding, MBA
Scottish National Blood Transfusion Service (UK)
Rosaria Giordano, MD
Fondazione IRCCS Ca’ Granda – Ospedale Maggiore Policlinico (IT)
Daniela Bischof, PhD
 Indiana University School of Medicine (US)

Gerhard Bauer, PhD
University of California Davis Institute for Regenerative Cures (US) 

See Session Details

Posters & Abstract Presentations

Poster Hall

18:00 – 19:30
Poster Session

Global Showcase Theatre (Exhibit Hall)

18:00 – 18:30
Abstract Elevator Pitch Session 1

SATURDAY MAY 30 - Day Three Main Meeting

08:00 - 09:00
Hot Topics Session

The spleen plays a critical role in modulating therapeutic outcomes following administration of cellular therapies in acute treatment settings

CHAIR
Robert (Willie) Mays, PhD
Athersys, Inc. (US)

SPEAKER
Richard Maziarz, MD
Oregon Health & Science University (US)

 

08:00 - 09:00
Hot Topics Session

Safety Matters for Regenerated Tissues
(Joint Session with TERMIS EU)

CO-CHAIRS
Ineke Slaper, Cortenbach, PhD
ICCBBA (NL)

Marina Marechal, PhD
KU Leuben (BE)

SPEAKERS
Ineke Slaper, Cortenbach, PhD
ICCBBA (NL)

Marina Marechal, PhD
KU Leuben (BE)

Julie Allickson, PhD
Wake Forest Institute for Regenerative Medicine (US)

08:00 - 09:00
Strategies for Commercialization

Providing effective cellular therapies in the face of commercialization – meeting patients’ needs and expectations

CHAIR
Gerhard Bauer, PhD
University of California, Davis Institute for Regenerative Cures (US)

SPEAKERS
Kathryn Rodden, BSc
QEHB NHS Foundation Trust (UK)

Mohamed Abou-El-Enein, MD, PhD
Charité – Universitätsmedizin Berlin (DE)

Mark Yarborough, PhD
University of California, Davis (US)

 

See Session Details

08:00 - 09:00
Quality & Operations

Characterization of Active Substance and Comparability

CHAIR
Rosemarie Bell, B.App.Sc Micro/Biochem MASM
Q-Gen Cell Therapeutics QIMR Berghofer Medical Research Institute (AU)

SPEAKERS
Mehrshid Alai-Safer, PhD
Kite Pharmaceuticals (US)

Mohamed Heidaran, PhD
Parexel International (US)

Krishnendu Roy, PhD
Georgia Institute of Technology (US)

See Session Details

09:15 – 10:45

Plenary
Gene Engineering: The Past, Present and the Future

See Session Details

CHAIR

S. Soni_cropped

Sandeep Soni, MD 
Stanford University (US)

translational research_cropped
D. Kohn_cropped

Donald Kohn, MD
University of California Los Angeles (US)

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P. Rio_cropped

Paula Rio, PhD
Centro de Investigaciones Energéticas
Medioambientales y Tecnológicas (CIEMAT) (SP)

clinical translation_cropped
C. Fonck_cropped

Carlos Fonck, PhD
DABT, BioMarin Pharmaceuticals Inc. (US)

10:45 – 11:00
Coffee Break

11:00 - 12:00
Plenary Satellite 5a

Gene Therapy Clinical Trials

11:00 - 12:00
Plenary Satellite 6a

EV Technical Session

CHAIR
Clotilde Thèry, PhD
Institut Curie, INSERM (FR)

SPEAKER
An Hendrix, PhD

Ghent University (BE)

See Session Details

11:00 - 12:00
Workshop

Late Breaking Oral Abstracts

11:00 - 12:00
Strategies for Commercialization

Clinical experience in regenerative medicine and tissue engineering, the next wave of advanced therapies

CHAIR
Julie Allickson, PhD
Wake Forest Institute for Regenerative Medicine (US)

SPEAKERS
Petter Björquist, PhD
VERIGRAFT AB (SE)
Martin Birchall, MD
University College London (UK)
Heather Prichard, PhD
Humacyte (US)

See Session Details

11:00 - 12:00
Quality & Operations

Analytical Tools and Method Development 

CHAIR
Gerry McKiernan
Cell Therapies Pty Ltd (AU)

SPEAKER
Sophie Paczensy, MD, PhD
Indiana University School of Medicine (US)

David M. Barrett, MD, PhD
Children’s Hospital of Philadelphia (US)

See Session Details

12:00 – 13:30
Lunch

12:15 – 13:15
ISCT Annual General Business Meeting
(All Members Invited)

13:30 – 15:00

Plenary
Basics and translational potential of extracellular vesicles including exosomes

See Session Details

CHAIR

B. Giebel

Bernd Giebel, PhD 
University Hospital Essen
Institute for Transfusion (DE)

translational research_cropped
C. Thery_cropped

Clotilde Théry, PhD
Institut Curie, INSERM (FR)

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SK. Lim_cropped

Sai-Kiang Lim, PhD
Institute of Medical Biology, A*STAR (SG)

translational research_cropped
R. Lim_cropped

Rebecca Lim, PhD
Monash University (AU)

15:00 – 15:15
Coffee Break

15:15 - 16:30
Plenary Satellite 5b

Ex-Vivo Stem Cell Based Clinical Trials

SPEAKER
Sandeep Soni, MD,
Stanford University (US) 

 

15:15 - 16:30
Plenary Satellite 6b

ISCT-ISEV Joint Session: MSC-EVs

SPEAKER
Mario Gimona, PhD
Paracelsus Medical University (AT)

15:15 - 16:30
Workshop

Early Stage Professionals Session

15:15 - 16:30
Strategies for Commercialization

Fast Track Regulations

CHAIR
Siofradh McMahon, MSc
CCRM (CA)

SPEAKER
Katy Spink, PhD
Dark Horse Consulting Group (US)

Eric Faulkner, MPH
Evidera (US)

See Session Details

15:15 - 16:30
Quality & Operations

GMP Manufacturing Challenges 

CHAIR
Shiraz Ziya, PhD, FRSA
Sartorius Stedim Biotech Ltd (UK)

SPEAKER
Angela Osborne, PhD
eXmoor pharma concepts ltd (UK)

Linda Kelley, PhD
Moffitt Cancer Center (US)

Suzanne Farid PhD, CEng, FIChemE
Dept. of Biochemical Engineering, UCL (UK)

Sarah Nikiforow MD, PhD
Dana-Farber Cancer Institute (US)

See Session Details